High Potency Compounds-Taking on the Challenge

Posted by Shelly James on Mar 13, 2018 2:00:00 PM

As a pharmaceutical or biotech company, if you haven't had to deal with high potency API (HPAPI) compounds yet, chances are you will eventually.  Approximately 25 percent of drugs in development worldwide are classified as highly potent, with this percentage expected to grow over the coming years; the global HPAPI market is expected to reach nearly $26 billion by 2022.

HPAPIs are a rapidly growing segment of the pharmaceutical industry, primarily due to an increased focus on targeted therapeutics, especially in oncology.  A compound is classified as highly potent if it has an occupational exposure limit (OEL) of ≤10μg/m3, a daily therapeutic dose of ≤10mg/day or if a 1 mg/kg/day dose produces serious toxicity in laboratory animals.

25% of drugs currently in development worldwide are highly potent.

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The Days of Clean Sheeting for Cost of Goods are Over.

Posted by David Perritt on Mar 5, 2018 9:30:00 AM

We have all been there when we need to determine various costs and where they come from.  We stare at spreadsheets, trying to gather the necessary data, critical and nonessential, and using our calculations to determine how we can lower costs.  This approach is not only time consuming, but inaccurate and inefficient, but what are the alternatives?

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DASH Diet: A Potential Treatment for Depression?

Posted by Rebecca James on Mar 2, 2018 1:00:00 PM

Physical health and mental health are definitively linked, and have been for some time. However, the extent that diet and exercise has on mental health remains unknown. There are anecdotes of certain diets lowering blood pressure by seemingly impossible amounts, diabetics claiming to be cured by their lifestyle and even claims of going into cancer remission as a result of a person’s diet.  None of these claims have been seriously substantiated, but recently a diet known as the DASH diet has been linked to lower blood pressure and decreased risk of depression.  Is it possible that something as simple and straightforward as your diet can affect your mental health?

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Topics: mental health, health

Flu Outbreak Worse This Year

Posted by Rebecca James on Feb 20, 2018 1:17:00 PM

This year's flu season has been unprecedentedly aggressive in comparison to recent years, causing levels of panic in the United States on the level of the H1N1 outbreak that occurred in 2009. Also known as swine flu, H1N1 caused rising levels of fear on a global level, with magazine covers publishing headlines about the epidemic and leading the World Health Organization to address the matter publicly, declaring it a pandemic.

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Topics: healthcare, flu, vaccination

Sanofi Pasteur Wrongdoing in Childrens Deaths?

Posted by Rebecca James on Feb 15, 2018 11:03:00 AM

In the Philippines, the government is currently dealing with a public health crisis surrounding the Dengue virus. After being inoculated with the Dengue vaccine known as Dengvaxia, children have fallen ill and succumbed to illness, some even falling sick to the Dengue virus within thirty days of their initial inoculation. 

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Topics: healthcare, ethics, vaccination

Is Excel Holding You Back?

Posted by David Perritt on Jan 22, 2018 9:26:00 AM

Is Excel a dated method of data crunching that is holding back rather than advancing your company? CFOs from Fortune 500 companies are insisting that staff stop using Excel. What does that mean for the pharmaceutical industry, and why is there push back against the popular spreadsheet software? Finance chiefs say the ubiquitous spreadsheet software that revolutionized accounting in the 1980s cannot kept up with the demands of contemporary corporate finance units. After all, just like hair metal bands, the 80s are long gone and pharmaceutical companies need to advance with the times.

Spreadsheets have been a necessary and advantageous tool in a huge number of industries. Excel has revolutionized accounting and driven decision making, but as business becomes more complex and global, Excel cannot bear the expectations and demands of many companies.

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Topics: Data Management, Cost Analysis, healthcare

Left Behind: Native American Healthcare

Posted by Rebecca James on Jan 12, 2018 10:30:00 AM

For many Native Americans, receiving healthcare can be a difficult ordeal. Poverty runs rampant on reservations throughout the United States, with one charity named One Spirit putting the number of Lakota families living under the poverty line in South Dakota at a staggering 90%. Even acquiring heating and basic living necessities is difficult for many of these families, reducing healthcare to a secondary concern. Native American people are at high risk for unnecessary death due to an intersection of unique situations such as isolation and poverty levels. 

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Topics: healthcare

Microfighters: Nanotechnology Takes on Cancer

Posted by Shelly James on Dec 13, 2017 11:37:00 AM

Cancer is a devastating disease, with approximately 40% of men and women facing a diagnosis of cancer at some point during their lifetimes (based on 2010-2012 data).  In addition, cancer is a costly disease, with national expenditures in the United States reaching nearly $125 billion in 2010 and a projected $156 billion in 2020.

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Topics: cancer, technology, chemotherapy

Autoimmune Disorder Treatment on the Horizon

Posted by Rebecca James on Nov 28, 2017 9:00:00 AM

Over 23.5 million Americans are afflicted with autoimmune diseases, including rheumatoid arthritis (RA)an autoimmune disease affecting approximately 1.3 million Americans.  In a case of mistaken identity, the body’s immune system mistakes its own tissues for foreign invaders, such as bacteria or viruses and develops antibodies to destroy the “invaders” in the synovium.  Currently, there is no cure for rheumatoid arthritis and the treatments are often saddled with a variety of side effects, some as severe as the disease.

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Topics: autoimmune disorders, development

Technology & Pharma: An Unexpected Intersection

Posted by Shelly James on Nov 10, 2017 11:00:00 AM

The pharmaceutical industry is currently in an era of change and in some senses is being upended by these changes, thanks to the development of new technology. Patients are rapidly becoming more empowered to do their own research and make decisions about their healthcare. One of the recent technological developments in the healthcare industry enabling this is the rise of the ‘health app’. Apple products have their own integrated health app that tracks statistics such as weight, heart rate, significant medical dates and other information. 

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Topics: technology